ExplanationExplanationThe Application Visibility and Control (AVC) engine lets you create policies to control application activity on the network without having to fully understand the underlying technology of each application. You can configure application control settings in Access Policy groups. You can block or allow applications individually or according to application type. You can also apply controls to particular application types.

A next-generation endpoint security solution is a modern approach of combining user and system behavior analytics with AI and machine learning to provide endpoint security12. These solutions are specifically designed to detect unknown malware and zero-day threats, which other non-next-generation solutions might fail to detect3. Two key deliverables that help justify the implementation of a next-generation endpoint security solution are:
* Continuous monitoring of all files that are located on connected endpoints. This feature allows the solution to scan and analyze all files on the endpoints, regardless of their origin or type, and identify any
* malicious or suspicious behavior. This helps to prevent malware from infecting the endpoints or spreading to other devices on the network4.
* Real-time feeds from global threat intelligence centers. This feature enables the solution to leverage the latest information and insights from various sources, such as security researchers, vendors, and customers, to detect and block new and emerging threats. This helps to keep the endpoints updated and protected from the most advanced and sophisticated attacks5.
References := 1: Overview of next-generation protection in Microsoft Defender for Endpoint 2: What Is Next-Generation Endpoint Security? 2024 Ultimate Guide - SelectHub 3: [Next

Cisco ISE allows a global configuration to issue a Change of Authorization (CoA) in the Profiler Configuration page that enables the profiling service with more control over endpoints that are already authenticated.
One of the settings to configure the CoA type is "Reauth". This option is used to enforce reauthentication of an already authenticated endpoint when it is profiled.
Reference:
b_ise_admin_guide_sample_chapter_010101.html