https://www.cisco.com/c/en/us/td/docs/routers/sdwan/configuration/segmentation/vEdge-20-x/segmentation-boo The Cisco vEdge platform supports IPv6 transport (WAN) as one of its features. This means that the vEdge routers can use IPv6 addresses to establish secure control and data plane connections with other vEdge routers over the WAN network. The vEdge routers can also use IPv6 addresses to communicate with the vSmart controllers and the vManage network management system. The vEdge routers can also support IPv6 routing protocols, such as OSPFv3 and BGP, to exchange IPv6 routes with other routers in the network12.
The other features listed in the question are not supported on the Cisco vEdge platform. License enforcement is not applicable to the vEdge routers, as they do not require any license to operate. Reporting is a function of the vManage network management system, which collects and displays various statistics and analytics from the vEdge routers. Non-Ethernet interfaces, such as serial, T1/E1, or DSL, are not available on the vEdge routers, which only support Ethernet and cellular interfaces. Single sign-on and 2-factor authentication are not supportedon the vEdge routers, which use local or remote authentication methods, such as TACACS+, RADIUS, or LDAP3.
References:
1: Cisco SD-WAN vEdge Routers Data Sheet 2: Cisco SD-WAN Configuration Guide, Release 20.3 3: Cisco SD-WAN Command Reference, Release 20.3

Cisco ISE benefits our customers by providing network access control and helping them stop and contain real-time threats. Network access control is the ability to enforce policies on who and what can access the network, based on the identity and context of users, devices, and applications. Cisco ISE allows customers to authenticate, authorize, and audit network access, as well as to segment and isolate network traffic based on security and compliance requirements. Cisco ISE also helps customers stop and contain real-time threats by leveraging intel from across the network and security ecosystem, and by automating threat response actions.
Cisco ISE can integrate with various security solutions, such as Cisco Stealthwatch, Cisco Firepower, and Cisco Umbrella, to detect and mitigate attacks on the network quickly and effectively. References:
* Cisco Identity Services Engine (ISE) - Cisco1
* Cisco Identity Services Engine (ISE) - Cisco2
* Network Visibility and Segmentation (NVS) - Cisco3
* Rapid Threat Containment - Cisco4
https://salesconnect.cisco.com/sc/s/learning-activity-from-plan?ltui__urlRecordId=a0c8c00000Kfw0AAAR&ltu Slide 3 - ISE is critical to your customer - * Visibility in to users, devices & applications * Access control and segmentation * Stop and contain threats in real-time