The best way to ensure that information system controls are effective is to test them periodically. Testing controls periodically helps to verify that the controls are operating as intended, and that they are aligned with the enterprise's objectives, policies, and standards. Testing controls periodically also helps to identify any gaps, weaknesses, or deficiencies in the controls, and to implement corrective actions or improvements.
Responding promptly to control exceptions, implementing compensating controls, and automating manual controls are good practices, but they are not the best way to ensure control effectiveness. References = Risk and Information Systems Control Study Manual, 7th Edition, Chapter 3, Section 3.1.1.2, page 1071
1: ISACA Certified in Risk and Information Systems Control (CRISC) Exam Guide, Answer to Question
641.

The primary risk management responsibility of the second line of defense is to monitor the risk responses.
The second line of defense is the function that oversees and supports the risk management activities of the first line of defense, which is the function that owns and manages the risks. The second line of defense includes the risk management, compliance, and quality assurance functions, among others. The second line of defense is responsible for monitoring the risk responses, which are the actions taken to address the risks, such as avoiding, transferring, mitigating, or accepting the risks. The second line of defense monitors the risk responses to ensure that they are implemented effectively and efficiently, that they achieve the desired outcomes, and that they are aligned with the risk appetite and tolerance of the organization. The second line of defense also provides guidance, advice, and feedback to the first line of defense on the risk responses, and reports the results and issues to the senior management and the board. Applying risk treatments, providing assurance of control effectiveness, and implementing internal controls are not the primary risk management responsibilities of the second line of defense, as they are either the responsibilities of the first line of defense or the third line of defense, which is the function that provides independent assurance of the risk management activities, such as the internal audit function. References = CRISC Review Manual, 6th Edition, ISACA,
2015, page 36.

The most important factor for sustainable development of secure IT services is security training for systems development staff. Security training helps to ensure that the staff members are aware of the security risks, requirements, and best practices that affect the IT services they develop. Security training also helps to improve the security skills and knowledge of the staff members, and to foster a security culture and behavior within the development team. Security training can also help to prevent or reduce security defects, vulnerabilities, or incidents in the IT services, and to enhance the security performance and quality of the IT services. Well-documented business cases, security architecture principles, and secure coding practices are also important factors for sustainable development of secure IT services, but they are not as important as security training for systems development staff. References = Risk and Information Systems Control Study Manual, 7th Edition, Chapter 5, Section 5.1.1.2, page 2291
1: ISACA Certified in Risk and Information Systems Control (CRISC) Exam Guide, Answer to Question
653.

Key control indicators are designed to measure the operational effectiveness of controls, specifically their contribution to defense-in-depth strategies. This helps assess if controls are functioning as intended to mitigate identified risks, aligning with Control Effectiveness Monitoring.

The best way to increase the chances of a successful delivery of a new application and to assure the business management that IT has a plan in place for early identification of potential issues is to include business management on a weekly risk and issues report. A risk and issues report is a document that summarizes the current status, progress, and challenges of the IT project, as well as the actions and resources needed to address them. A risk and issues report helps to communicate and align the expectations and objectives of the IT and business stakeholders, and to facilitate timely and effective decision-making and problem-solving. A risk and issues report also helps to monitor and control the project scope, schedule, budget, and quality, and to ensure that the project delivers the desired value and benefits to the organization. The other options are not as effective as including business management on a weekly risk and issues report, although they may be part of the IT project management process or outcomes. Implementing a release and deployment plan, conducting comprehensive regression testing, and developing enterprise-wide key risk indicators (KRIs) are all activities that can help to ensure the quality and reliability of the new application, but they do not necessarily involve the business management or provide assurance for the early identification of potential issues. References = Risk and Information Systems Control Study Manual, Chapter 5, Section 5.4.1, page 5-32.