Explanation
A unique secondary key is a type of secondary key that ensures that the key combination of all the rows in a table is unique. A unique secondary key has two purposes: firstly, to speed up access to the table, and secondly, to enforce data integrity1.
It is created with the first read access of a table: This is true. A unique secondary key is created when an internal table is filled for the first time using the statement READ TABLE or a similar statement. The system assigns a name and an index to each row of the table based on the key fields23.
It is updated when the modified table is read again: This is false. A unique secondary key does not need to be updated when the internal table content changes, because it already ensures data uniqueness. The system uses a lazy update strategy for non-unique secondary keys, which means that it delays updating them until they are actually accessed23.
You cannot do any of the following:
It is created when a table is filled: This is false. As explained above, a unique secondary key is created only with the first read access of a table23.
It is updated when the modified table is read again: This is false. As explained above, a unique secondary key does not need to be updated when the internal table content changes23.
References: 1: Improving Internal Table Performance Using Secondary Keys - SAP Learning 2: [Secondary Key - ABAP Keyword Documentation - SAP Online Help] 3: [Secondary Table Key - ABAP Keyword Documentation - SAP Online Help]

A unique secondary key is a type of secondary key that ensures that the key combination of all the rows in a table is unique. A unique secondary key has two purposes: firstly, to speed up access to the table, and secondly, to enforce data integrity1.
It is created with the first read access of a table: This is true. A unique secondary key is created when an internal table is filled for the first time using the statement READ TABLE or a similar statement. The system assigns a name and an index to each row of the table based on the key fields23.
It is updated when the modified table is read again: This is false. A unique secondary key does not need to be updated when the internal table content changes, because it already ensures data uniqueness. The system uses a lazy update strategy for non-unique secondary keys, which means that it delays updating them until they are actually accessed23.
You cannot do any of the following:
It is created when a table is filled: This is false. As explained above, a unique secondary key is created only with the first read access of a table23.
It is updated when the modified table is read again: This is false. As explained above, a unique secondary key does not need to be updated when the internal table content changes23.

The ABAP Cloud Development Model requires that only public SAP APIs and extension points are used to access SAP functionality and data. These APIs and extension points are released by SAP and documented in the SAP API Business Hub1. Customer-created function modules are not part of the public SAP APIs and are not released for cloud development. Therefore, calling a function module directly from an ABAP Cloud class is not allowed and will result in a syntax error. However, there are two possible ways to call a function module indirectly from an ABAP Cloud class:
* Create a wrapper class or interface for the function module and release it for cloud development. A wrapper is a class or interface that encapsulates the function module and exposes its functionality through public methods or attributes. The wrapper must be created in a software component with the language version set to "Standard ABAP" and must be marked as released for cloud development using the annotation @EndUserText.label. The wrapper can then be called from an ABAP Cloud class using the public methods or attributes2.
* Use the ABAP Cloud Connector to call the function module as a remote function call (RFC) from an ABAP Cloud class. The ABAP Cloud Connector is a service that enables the secure and reliable communication between SAP BTP, ABAP environment and on-premise systems. The function module must be exposed as an RFC-enabled function module in the on-premise system and must be registered in the ABAP Cloud Connector. The ABAP Cloud class can then use the class cl_rfc_destination_service to get the destination name and the class cl_abap_system to create a proxy object for the function module. The proxy object can then be used to call the function module3.
References: 1: SAP API Business Hub 2: Creating an ABAP Cloud Project | SAP Help Portal 3: Calling Remote Function Modules | SAP Help Portal

Both statements are valid in ABAP, but they have different effects on the program.
##NEEDED is a pragma that can be used to hide warnings from the ABAP compiler syntax check. It tells the check tools that a variable or a parameter is needed for further processing, even if it is not used in the current statement. For example, if you declare a variable without assigning any value to it, you can use ##NEEDED to suppress the warning about unused variables12.
The pragma is not checked by the syntax checker means that you can use any pragma to hide any warning from the ABAP compiler syntax check, regardless of its effect on the program logic or performance. For example, if you use ##SHADOW to hide a warning about an obscured function, you can also use it to hide a warning about an invalid character in a string12.
You cannot do any of the following:
#EC_NEEDED is not checked by the syntax checker: This is not a valid statement in ABAP. There is no pseudo-comment with #EC_NEEDED in ABAP3.
The pseudo-comment is checked by the syntax checker: This is false. Pseudo-comments are obsolete and should no longer be used in ABAP. They were replaced by pragmas since SAP NW 7.0 EhP2 (Enhancement Package)4.

The RESTful Application Programming feature that is used to ensure the uniqueness of a semantic key is determination. A determination is a type of behavior implementation that defines a logic that is executed automatically when certain events occur, such as create, update, delete, or activate. A determination can be used to calculate or derive values for certain fields, such as semantic keys, based on other fields or external sources. A determination can also be used to check the uniqueness of a semantic key by comparing it with the existing values in the database or the transaction buffer. A determination can use the ABAP SQL or the EML syntax to access and manipulate data. A determination can be defined using the DETERMINE action clause in the behavior definition of a CDS view entity or a projection view. A determination can also be annotated with the @ObjectModel.determination annotation to specify the event, the timing, and the scope of the determination12 The other RESTful Application Programming features are not used to ensure the uniqueness of a semantic key, but have different purposes and effects. These features are:
Validation: A validation is a type of behavior implementation that defines a logic that is executed automatically when certain events occur, such as create, update, delete, or activate. A validation can be used to check the consistency and correctness of the data, such as mandatory fields, data types, value ranges, or business rules. A validation can use the ABAP SQL or the EML syntax to access and manipulate data. A validation can be defined using the VALIDATE action clause in the behavior definition of a CDS view entity or a projection view. A validation can also be annotated with the @ObjectModel.validation annotation to specify the event, the timing, and the scope of the validation12 Action: An action is a type of behavior implementation that defines a logic that is executed explicitly by the user or the application. An action can be used to perform a specific business operation, such as creating, updating, deleting, or activating an entity instance, or triggering a workflow or a notification. An action can use the ABAP SQL or the EML syntax to access and manipulate data. An action can be defined using the ACTION clause in the behavior definition of a CDS view entity or a projection view. An action can also be annotated with the @ObjectModel.action annotation to specify the name, the description, the parameters, and the visibility of the action12