Online Access Free ABMM Exam Questions

The primary mechanism of action of aminoglycoside antibiotics, such as gentamicin, involves:

• A.Inhibition of bacterial DNA gyrase and topoisomerase IV
• B.Inhibition of bacterial cell wall synthesis by binding to penicillin-binding proteins
• C.Disruption of bacterial cell membrane integrity
• D.Inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit

The gut microbiome has been implicated in the pathogenesis of autoimmune diseases. Dysbiosis, a disruption in the composition and function of the gut microbiota, can lead to increased intestinal permeability and the translocation of microbial products that trigger inflammatory responses. Which of the following bacterial components is a potent activator of the innate immune system and has been linked to the development of autoimmunity?

• A.Lipopolysaccharide (LPS)
• B.Lipoteichoic acid (LTA)
• C.Flagellin
• D.Peptidoglycan

A patient develops a severe diarrheal illness after returning from a backpacking trip where they drank untreated stream water. Stool examination reveals motile trophozoites with multiple flagella and a prominent ventral sucking disk. The MOST likely causative agent is:

• A.Giardia lamblia
• B.Entamoeba histolytica
• C.Cyclospora cayetanensis
• D.Cryptosporidium parvum

A laboratory worker sustains a needlestick injury while handling a blood sample known to be positive for Hepatitis B surface antigen (HBsAg) and Hepatitis B e antigen (HBeAg). The worker has completed the HBV vaccination series and has a documented anti-HBs titer >10 mIU/mL one month ago. What is the recommended post-exposure prophylaxis?

• A.Hepatitis B immune globulin (HBIG) only
• B.Both HBIG and HBV vaccine booster dose
• C.No treatment required
• D.Hepatitis B vaccine booster dose only

A fungal isolate grown from a blood culture at 37°C shows budding yeast cells. When subcultured to cornmeal agar with Tween 80 and incubated at 25°C, it produces pseudohyphae and terminal chlamydospores.
Growth on CHROMagar Candida yields green colonies. This organism is most likely:

• A.Candida glabrata
• B.Candida albicans
• C.Candida parapsilosis
• D.Cryptococcus neoformans