A patient with renal failure is being treated with phenytoin and has an albumin concentration of
1.7 g/dL. Which of the following is likely to be higher than the general population in this patient?

The prophylaxis of postsurgical deep vein thrombosis was reviewed in an article published 5 years ago. A researcher wishes to identify any studies since then that have used this article as a reference. What is the most appropriate database for this search?

A prospective randomized study is being developed to evaluate the effects of steroids on mortality in patients who are admitted for head injury Patients will be randomly assigned to receive 48 hours of methylprednisolone or placebo. The study will have an 80% power to detect a 2% difference in mortality. Which of the following is an appropriate null hypothesis for this study?

A 65-year-old woman on chronic hemodialysis presents with difficulty breathing and inability to sleep. The patient has had shortness of breath, diaphoresis, and nausea, but has not vomited.
She denies having abdominal pain, diarrhea, or chest pain. She has tachycardia and tachypnea, and exhibits peaked T waves with occasional PVCs on the ECG. Serum chemistry values are:
* Sodium: 137 mEq/L
* BUN: 125 mg/dL
* Potassium: 7.2 mEq/L
* Creatinine: 12.8 mg/dL
* Chloride: 97 mEq/L
* Glucose: 95 mg/dL
* HCO3- : 11 mEq/L
* Calcium: 8.5 mg/dL
* Albumin: 3.1 g/dL
* Phosphorus: 1.7 mg/dL
Which of the following should the pharmacotherapy specialist recommend for immediate therapy?

A 65-year-old Woman presents with complaints of Worsening incontinence associated with sneezing and coughing, as well as itching in the genital area. Physical examination reveals some vaginal atrophy. A pad test is positive, post void residuals average 5 mL, and urinalysis is normal. Which of the following is the best treatment option for this patient?