Advanced Malware Protection (AMP) for Endpoints offers a variety of lists, referred to as Outbreak Control, that allow you to customize it to your needs. The main lists are: Simple Custom Detections, Blocked Applications, Allowed Applications, Advanced Custom Detections, and IP Blocked and Allowed Lists.
A Simple Custom Detection list is similar to a blocked list. These are files that you want to detect and quarantine.
Allowed applications lists are for files you never want to convict. Some examples are a custom application that is detected by a generic engine or a standard image that you use throughout the company Reference: https://docs.amp.cisco.com/AMP%20for%20Endpoints%20User%20Guide.pdf