An IT balanced scorecard is a strategic management tool that aligns IT objectives with business goals and measures the performance of IT processes using key performance indicators (KPIs). It is the most effective means of monitoring governance of enterprise IT, which is the process of ensuring that IT supports the organization's strategy and objectives. Governance of enterprise IT covers aspects such as IT value delivery, IT risk management, IT resource management, and IT performance measurement. An IT balanced scorecard can help monitor these aspects and provide feedback to improve IT governance. References: ISACA Frameworks: Blueprints for Success, CISA Review Manual (Digital Version)

The greatest challenge to the alignment of business and IT is the lack of chief information officer (CIO) involvement in board meetings. The CIO is the senior executive responsible for overseeing the IT strategy, governance, and operations of the organization, and ensuring that they support the business objectives and needs. The CIO should be involved in board meetings to communicate the value and contribution of IT to the organization, to align the IT vision and direction with the business strategy and priorities, and to advocate for the IT resources and investments required to achieve the desired outcomes. The lack of CIO involvement in board meetings can result in a disconnect between business and IT, a loss of trust and confidence in IT, and missed opportunities for innovation and value creation. The other options are not as challenging as the lack of CIO involvement in board meetings, because they either do not affect the strategic alignment of business and IT, or they can be addressed by other means such as collaboration, negotiation, or escalation. References:
CISA Review Manual (Digital Version)1, Chapter 1, Section 1.2.1

The greatest concern for an IS auditor if there are flaws in the mapping of accounts between a front-end subledger and a main ledger is the inaccuracy of financial reporting. A subledger is a detailed record of transactions for a specific account, such as accounts receivable, accounts payable, inventory, or fixed assets.
A main ledger is a summary record of all transactions for all accounts in an accounting system. The mapping of accounts between a subledger and a main ledger is the process of linking or reconciling the transactions in the subledger with the corresponding entries in the main ledger. If there are flaws in the mapping of accounts, such as missing, duplicated, or incorrect transactions, the main ledger may not reflect the true financial position and performance of the organization. This may lead to inaccurate financial reporting, which may affect decision making, compliance, auditing, taxation, and stakeholder confidence.
Double-posting of a single journal entry, inability to support new business transactions, and unauthorized alteration of account attributes are not the greatest concerns for an IS auditor if there are flaws in the mapping of accounts between a front-end subledger and a main ledger. These are possible consequences or causes of flaws in the mapping of accounts, but they do not have as significant an impact as inaccuracy of financial reporting. Double-posting of a single journal entry may result in errors or discrepancies in the main ledger balances. Inability to support new business transactions may indicate limitations or inefficiencies in the accounting system design or configuration. Unauthorized alteration of account attributes may suggest weaknesses or breaches in access control or segregation of duties.

Continuous auditing provides the greatest assurance that a middleware application compiling data from multiple sales transaction databases for forecasting is operating effectively12. Continuous auditing involves the use of automated tools to continuously monitor and audit a system's operations12. This allows for real- time identification and resolution of issues, ensuring that the system is always functioning as expected12. It also provides ongoing assurance about the integrity and reliability of the data being compiled by the middleware application12.
References:
5 Data Integration Methods and Strategies | Talend
What Is Middleware? Definition, Architecture, and Best Practices